ea0011p640 | Neuroendocrinology and behaviour | ECE2006
Hoybye C
Objective: Prader-Willi syndrome (PWS) is a complex genetic disorder. Body composition abnormalities, hyperphagia, progressive obesity and diminished growth hormone secretion are common. In a previous one year GH intervention trial in 19 PWS adults, we have shown beneficial effects on body composition. In the present study we sought to re-evaluate the cohort, with special emphasis on long-term effects of GH treatment.Methods: Fourteen patients, 7 men and...